BioFlux Online Webinars
Attend live webinars by customers or Fluxion scientists about different research and techniques being implemented with the BioFlux system. All online Webinars are recorded for later viewing. The above are only a few of the webinars found in our online Webinar Library.
Check this page regularly for upcoming online webinars, when one is scheduled, information and registration will appear below.
UPCOMING ONLINE WEBINAR
RECORDED ONLINE WEBINARS
BIOFLUX SYSTEM IN CIRCULATING TUMOR CELLS RESEARCH
Presented on June 1st 2016
Dr. Bryan Haines, PhD
BioFlux Technical Director
The adhesion of circulating cancer cells to vascular endothelium is a key step in metastasis. Understanding this process has the potential to impact the risk of metastasis in cancer patients. Dr. Haines will explain the benefits of using BioFlux to study circulating tumor cell adhesion under physiological flow and review the recent studies in this area
CAN MICROFLUIDIC FLOW-BASED DIAGNOSTICS PERSONALIZE THERAPY IN SICKLE CELL DISEASE? A VISION FOR THE FUTURE
Presented on January 27 2016
Dr. Patrick Hines, MD/PhD
Pediatric Critical Care Medicine Physician, Pulmonary Hypertension Specialist, and Vascular Biology Research Scientist
James Herrick’s first described the “Peculiar Elongated and Sickle-Shaped Red Blood Corpuscles in a Case of Severe Anemia” in 1910. Linus Pauling discovered the molecular basis for sickle cell disease (SCD) in 1949. Since these landmark discoveries, there has only been one FDA-approved therapy for the prevention of SCD-related complications. Fortunately, this is an historic moment in sickle cell discovery with the largest pipeline of promising SCD-specific drugs in preclinical and clinical trials in the history of the disease. In addition to targeting hemoglobin polymerization, many of these drugs target the unique erythrocyte adhesive properties that contribute to microvascular obstruction. Despite this, there is no clinical standard for assessing erythrocyte adhesion. SCD providers will soon have drugs available to prevent and relieve adhesion-mediated complications, therefore there is an urgent need diagnostic tools to guide drug selection for individual patients and monitor therapeutic response. Dr. Hines has used flow adhesion models to understand the adhesive properties of sickle erythrocytes in a simulated blood flow environment, and has worked to standardize this process for clinical testing. He recently founded Functional Fluidics, a startup company who has deployed a standardized microfluidic flow-based test into the preclinical and clinical research market. Dr. Hines will discuss advances in microfluidic flow-based blood function testing, the role these tests are play in preclinical drug validation, and the potential for applications in sickle cell clinical trials and ultimately clinical therapy.
BIOFLUX WEBINAR: USING BIOFLUX TO STUDY CELL ROLLING
Presented on October 22 2015
Dr. Bryan Haines from Fluxion Biosciences presents a a BioFlux webinar focusing on setting and analyzing cell rolling experiments
STUDYING FUNGUS-BACTERIUM INTERACTIONS UNDER DYNAMIC CONDITIONS
Presented on February 5 2015
Dr. Bastiaan P. Krom Ph.D.
Associate Professor of Preventive Dentistry
Department of Preventive Dentistry, Academic Centre for Dentistry Amsterdam (ACTA)
University of Amsterdam and Free University Amsterdam
Amsterdam, The Netherlands.
The fungus Candida albicans is a commensal to most, if not all, mammals. This versatile fungus thrives in diverse niches of humans such as the skin, GI-tract, vagina and the oral cavity. In all of these niches it encounters different bacteria. It is therefore not surprising that C. albicans has developed specific systems to interact with co-inhabiting bacteria. These interactions can be chemical (signaling and metabolic) or physical (adhesion and aggregation) in nature. In this webinar I will present approaches we currently use to study dynamics of these interactions and their biological function. In particular I will focus on real-time analysis of bacterial adhesion to C. albicans and on the effect of fungus-bacterium interactions in relation to macrophage function. In addition, I will discuss how we study the effect of bacterial small molecules on fungal behavior.