BioFlux Webinar: Studying fungus-bacterium interactions under dynamic conditions

Join Dr. Bastiaan P. Krom from the Academic Centre for Dentistry Amsterdam (ACTA) for an online Webinar featuring BioFlux systems.

Speaker:
Dr. Bastiaan P. Krom Ph.D.
Associate Professor of Preventive Dentistry
Department of Preventive Dentistry, Academic Centre for Dentistry Amsterdam (ACTA)
University of Amsterdam and Free University Amsterdam
Amsterdam, The Netherlands.
E-mail: b.krom@acta.nl
 
Abstract:
The fungus Candida albicans is a commensal to most, if not all, mammals. This versatile fungus thrives in diverse niches of humans such as the skin, GI-tract, vagina and the oral cavity. In all of these niches it encounters different bacteria. It is therefor not surprising that C. albicans has developed specific systems to interact with co-inhabiting bacteria. These interactions can be chemical (signaling and metabolic) or physical (adhesion and aggregation) in nature. In this webinar I will present approaches we currently use to study dynamics of these interactions and their biological function. In particular I will focus on real-time analysis of bacterial adhesion to C. albicans and on the effect of fungus-bacterium interactions in relation to macrophage function. In addition, I will discuss how we study the effect of bacterial small molecules on fungal behavior.