Subscribe to this pageIonFlux System

 Product Information (4 items)
IonFlux F1 Giga-Ohm Seal Plates   (Adobe PDF, 139 KBytes)
IonFlux Product Brochure   (Adobe PDF, 1.3 MBytes)
IonFlux Product Data Sheet   (Adobe PDF, 856 KBytes)
IonFlux Well Plate Layout   (Adobe PDF, 304 KBytes)
A technical note describing the microfluidic layout on the 96- and 384-well IonFlux Plates.
 Publications (2 items)
Assay and Drug Development Publication - hERG application   (Adobe PDF, 54 KBytes)
Publication from Novartis on hERG applications using the IonFlux System.
Electrophoresis-assisted Single Cell Electroporation (Biomed Devices)   (Adobe PDF, 184 KBytes)
A paper published in Biomedical Microdevices highlighting a novel technique for efficient intracellular delivery.
 Application Notes (9 items)
Transiently Transfected Cell Lines for GABA Receptor Screening using the IonFlux System   (Adobe PDF, 213 KBytes)
Endogenous GABA-A Channels   (Adobe PDF, 460 KBytes)
NMDA Receptor - Validation Data   (Adobe PDF, 323 KBytes)
Temperature Dependent hERG Channel Pharmacology and Kinetics on the IonFlux System   (Adobe PDF, 337 KBytes)
The IonFlux system integrates a temperature control module, enabling users to perform temperature dependent electrophysiology screening assays. In this report, we present pharmacology and kinetic data from the hERG channel, comparing room temperature to physiological temperature recordings on the IonFlux platform.
Cell Lines and Ion Channels on IonFlux   (Adobe PDF, 176 KBytes)
Contains a list of cell lines and ion channel targets which have been tested and validated on the IonFlux System.
Nicotinic Acetylcholine Receptors Application Note   (Adobe PDF, 804 KBytes)
hERG Application Note   (Adobe PDF, 835 KBytes)
Here we present results of recordings of hERG currents expressed in mammalian cell cultures and the pharmacological inhibition profiles of a panel of drug compounds using the IonFlux system.
Nav1.7 and Nav1.8 Recordings on the IonFlux System   (Adobe PDF, 266 KBytes)
Overview of Nav1.7 and Nav1.8 current recordings and pharmacology of lidocaine.
GABA-A Application Note   (Adobe PDF, 622 KBytes)
An overview presentation of GABA-A application data, including success rates, assay repeatability, and pharmacology for a number of positive and negative GABA-A receptor modulators.
 Poster Presentations (6 items)
IonFlux Poster Presentation - Ligand and Voltage Gated Channels   (Adobe PDF, 1017 KBytes)
SBS 2010 Poster Presentation
IONFLUX: A MICROFLUIDIC APPROACH TO ENSEMBLE RECORDING AND BLOCK OF WHOLE-CELL CURRENT FROM VOLTAGE-GATED ION CHANNELS   (Adobe PDF, 3.4 MBytes)
Biophysics 2010 Poster Presentation
AN ELECTROPHYSIOLOGY ASSAY FOR THE FAST CHARACTERIZATION OF GABA ION CHANNEL MODULATORS   (Adobe PDF, 1.3 MBytes)
Biophysics 2010 Poster Presentation
A HIGH THROUGHPUT MICROFLUIDIC APPROACH ENABLES FAST EXCHANGE OF SOLUTIONS AND LIGAND GATED ION CHANNEL RECORDING FROM CELL ENSEMBLE   (Adobe PDF, 1.4 MBytes)
Biophysics 2010 Poster Presentation
Enabling “Plate Reader” Simplicity in High Throughput Electrophysiology (Aurora 2009 Poster)   (Adobe PDF, 578 KBytes)
SBS Poster 2008 - High Throughput Electrophysiology   (Adobe PDF, 258 KBytes)
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